What is the CNODES Common Data Model (CDM) project?
The CNODES Common Data Model (CDM) was adapted from the FDA Sentinel CDM. This standardized data structure allows data centres to execute distributed computer programs against their local data to generate common output tables, which can then be pooled to give aggregate, multi-centre results. The main advantages of the CDM are the short time frame needed to process queries across multiple data centres, and output quality control.
What CNODES data centres are involved in the CDM Project?
The CNODES data centres in British Columbia, Alberta, Saskatchewan, Manitoba, Ontario and Nova Scotia transformed their provincial administrative databases into the CDM and are ready to receive queries that can be completed using the CDM.
What types of studies can be conducted with the CDM project and how long do they take?
The CDM can provide rapid analyses of prescription medication use, patient characteristics, apparent indications for drug therapy, clinical outcomes and health service use following drug treatment. A CDM Mother-Infant table is available for studies of pregnancy drug exposure safety. A COVID-19 laboratory test table is available in British Columbia, Manitoba, and Ontario. Currently, the prescription drug claims contained in the CNODES CDM do not include vaccines, infused chemotherapies or medications administered to hospital inpatients.
Examples of the wide range of CDM studies undertaken within the U.S. Sentinel CDM are available on the Sentinel website.
The timeline for completion of a CNODES CDM query is 10-20 weeks, depending on the number of data centres involved.
Collaboration with the U.S. FDA Sentinel Initiative
CNODES collaborates with the FDA Sentinel Initiative to facilitate cooperative research projects between Health Canada and FDA.
