Our studies begin with a question (referred to as a query) concerning the safety, effectiveness or utilization of a medication or class of medications submitted by one of our partners: Health Canada, provincial and territorial drug plan managers, or the Canadian Agency for Drugs and Technologies in Health (CADTH). These requests are sent to DSEN, who then evaluate and assign these queries to one of their research teams, including CNODES (see the organizational chart of DSEN here). Results from our studies go on to inform policy makers, healthcare providers, regulators and patients on the safety and effectiveness of drugs. Our findings are also published in leading academic journals.