10 Jul Pierre Ernst
Bio
Pierre Ernst graduated in Medicine from Université de Montreal, completed internal medicine and pulmonary training at McGill University, after which he completed an M.Sc in Epidemiology and Biostatistics at McGill. He is currently an attending physician in the Pulmonary Division of the Department of Medicine at the Jewish General Hospital and a Professor of Medicine at McGill University.
Dr. Ernst’s current research activities focus on the safety of medications as used in the general population after approval for commercialization. He has been extensively involved in CNODES as a member of the CNODES Steering Committee, the Database Team, the Training Team and the Policies and Procedures Committee. He has participated in multiple CNODES projects and was the senior investigator on six.
CNODES Projects
- Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort studyProject Co-Lead, CPRD
- Association between incretin-based drugs and the risk of acute pancreatitisProject Co-Lead
- Ventricular tachyarrhythmia and sudden cardiac death with domperidone use in Parkinson’s DiseaseSite Investigator, CPRD
- A multicenter observational study of incretin-based drugs and heart failureProject Co-Lead
- Serotonin-norepinephrine reuptake inhibitors and the risk of AKI: A cohort study of eight administrative databases and meta-analysisProject Lead
- Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysisSite Investigator, CPRD
- Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databasesSite Investigator, CPRD
- Site Investigator, CPRD
- Steering Committee Liaison
- Impact of using concomitant conventional DMARDs on adherence to biologic DMARD treatment in rheumatoid arthritis: Multi-centre, population-based cohort studySteering Committee Liaison
- Comparative safety of direct oral anticoagulants and warfarin in patients with venous thromboembolism: a multicenter observational study of administrative databasesSteering Committee Liaison
- Comparative effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists in nonvalvular atrial fibrillation: a Canadian multicentre observational cohort studySteering Committee Liaison
- Confounding by drug formulary restriction in pharmacoepidemiologic researchCollaborator, CPRD
- Major bleeding in users of direct oral anticoagulants in atrial fibrillation: A pooled analysis of results from multiple population-based cohort studiesProject Lead
- Sodium glucose cotransporter 2 inhibitors and risk of major adverse cardiovascular events: multi-database retrospective cohort studyProject Lead
- Sodium-glucose co-transporter-2 inhibitors and the risk of urosepsis: A multi-site, prevalent new-user cohort studyProject Lead
- Sodium-glucose cotransporter 2 inhibitors and the risk of below-knee amputation: a multicenter observational studyProject Lead
- Sodium-glucose cotransporter-2 inhibitors and the risk for diabetic ketoacidosis: a multicenter cohort studyProject Lead
- Use of systemic oral fluoroquinolones in CanadaSteering Committee Liaison
- Fluoroquinolone use for uncomplicated urinary tract infections in women: a retrospective cohort studySteering Committee Liaison
- Fluoroquinolone use for acute bacterial sinusitisSteering Committee Liaison
- Comparative effectiveness of fluoroquinolone antibiotic use in uncomplicated acute exacerbations of chronic obstructive pulmonary disease: a multi-cohort studySteering Committee Liaison
- Characteristics of new users of newer antidiabetic drugs in Canada and the United KingdomProject Lead
- Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort studyCollaborator, CPRD
- Effectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi-database cohort study with meta-analysisSteering Committee Liaison
- Project Lead
- Use of proton pump inhibitors and development of acute myocardial infarctionCo-Site Investigator, Quebec
- Proton pump inhibitors and the risk of Clostridium difficile infectionCo-Site Investigator, Quebec
- Use of Oral Fluoroquinolones in Canada: A Drug Utilization Study UpdateProject Lead
 
 			 