10 Jul Pierre Ernst
Bio
Pierre Ernst graduated in Medicine from Université de Montreal, completed internal medicine and pulmonary training at McGill University, after which he completed an M.Sc in Epidemiology and Biostatistics at McGill. He is currently an attending physician in the Pulmonary Division of the Department of Medicine at the Jewish General Hospital and a Professor of Medicine at McGill University.
Dr. Ernst’s current research activities focus on the safety of medications as used in the general population after approval for commercialization. He has been extensively involved in CNODES as a member of the CNODES Steering Committee, the Database Team, the Training Team and the Policies and Procedures Committee. He has participated in multiple CNODES projects and was the senior investigator on six.
CNODES Projects
Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study
Project Co-Lead, CPRDAssociation between incretin-based drugs and the risk of acute pancreatitis
Project Co-LeadVentricular tachyarrhythmia and sudden cardiac death with domperidone use in Parkinson’s Disease
Site Investigator, CPRDA multicenter observational study of incretin-based drugs and heart failure
Project Co-LeadSerotonin-norepinephrine reuptake inhibitors and the risk of AKI: A cohort study of eight administrative databases and meta-analysis
Project LeadProton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis
Site Investigator, CPRDUse of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Site Investigator, CPRD- Site Investigator, CPRD
- Steering Committee Liaison
Impact of using concomitant conventional DMARDs on adherence to biologic DMARD treatment in rheumatoid arthritis: Multi-centre, population-based cohort study
Steering Committee LiaisonComparative safety of direct oral anticoagulants and warfarin in patients with venous thromboembolism: a multicenter observational study of administrative databases
Steering Committee LiaisonComparative effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists in nonvalvular atrial fibrillation: a Canadian multicentre observational cohort study
Steering Committee LiaisonConfounding by drug formulary restriction in pharmacoepidemiologic research
Collaborator, CPRDMajor bleeding in users of direct oral anticoagulants in atrial fibrillation: A pooled analysis of results from multiple population-based cohort studies
Project LeadSodium glucose cotransporter 2 inhibitors and risk of major adverse cardiovascular events: multi-database retrospective cohort study
Project LeadSodium-glucose co-transporter-2 inhibitors and the risk of urosepsis: A multi-site, prevalent new-user cohort study
Project LeadSodium-glucose cotransporter 2 inhibitors and the risk of below-knee amputation: a multicenter observational study
Project LeadSodium-glucose cotransporter-2 inhibitors and the risk for diabetic ketoacidosis: a multicenter cohort study
Project LeadUse of systemic oral fluoroquinolones in Canada
Steering Committee LiaisonFluoroquinolone use for uncomplicated urinary tract infections in women: a retrospective cohort study
Steering Committee LiaisonFluoroquinolone use for acute bacterial sinusitis
Steering Committee LiaisonComparative effectiveness of fluoroquinolone antibiotic use in uncomplicated acute exacerbations of chronic obstructive pulmonary disease: a multi-cohort study
Steering Committee LiaisonCharacteristics of new users of newer antidiabetic drugs in Canada and the United Kingdom
Project LeadValidity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study
Collaborator, CPRDEffectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi-database cohort study with meta-analysis
Steering Committee Liaison- Project Lead
Use of proton pump inhibitors and development of acute myocardial infarction
Co-Site Investigator, QuebecProton pump inhibitors and the risk of Clostridium difficile infection
Co-Site Investigator, QuebecUse of Oral Fluoroquinolones in Canada: A Drug Utilization Study Update
Project Lead