14 Jul Michael Paterson
Bio
Michael joined the Institute for Clinical Evaluative Sciences as an Epidemiologist in 1992 and became an ICES Scientist and Research Program Lead in 2008. He is an Assistant Professor in both the Department of Family Medicine at McMaster University and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He holds a Bachelor’s degree in Human Biology from the University of Guelph and a Master’s degree in Physiology from the University of Toronto.
Michael has been Principal Investigator for the Ontario site of CNODES since its inception, and has served as a Site Liaison and co-author on multiple CNODES projects. Michael is currently a member of the CNODES Steering Committee, Database Team, Training Team, and Knowledge Translation Team.
In addition to his work with CNODES, Michael is an active member of the Ontario Ministry of Health and Long-Term Care-funded Ontario Drug Policy Research Network (ODPRN, www.odprn.ca). Michael has received over 60 research grants and has authored over 200 peer-reviewed publications in the fields of health services research, drug safety and drug policy, including a 2011 article that was named one of the “Twenty top papers to mark The BMJ’s two digital decades”.
CNODES Projects
Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study
Site Investigator, OntarioA multicenter observational study of incretin-based drugs and heart failure
Site Investigator, OntarioSerotonin-norepinephrine reuptake inhibitors and the risk of AKI: A cohort study of eight administrative databases and meta-analysis
Site Investigator, OntarioHigher potency statins and the risk of new diabetes: multicentre, observational study of administrative databases
Site Investigator, OntarioProton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis
Collaborator, OntarioUse of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Site Investigator, OntarioOccurrence of pregnancy and pregnancy outcomes during isotretinoin therapy
Co-Site Investigator, OntarioAtypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data
Site Investigator, OntarioImpact of using concomitant conventional DMARDs on adherence to biologic DMARD treatment in rheumatoid arthritis: Multi-centre, population-based cohort study
Site Investigator, OntarioComparative safety of direct oral anticoagulants and warfarin in patients with venous thromboembolism: a multicenter observational study of administrative databases
Site Investigator, OntarioComparison of pregnancy outcomes of patients treated with ondansetron vs alternative antiemetic medications in a multinational, population-based cohort
Site Investigator, OntarioUtilization and adverse outcomes of fluconazole during pregnancy
Project Co-LeadUtilization and adverse outcomes of fluconazole during pregnancy
Site Investigator, OntarioMajor bleeding in users of direct oral anticoagulants in atrial fibrillation: A pooled analysis of results from multiple population-based cohort studies
Site Investigator, OntarioCNODES simulated data platform
CollaboratorData variability across Canadian administrative health databases: Differences in content, coding, and completeness
Collaborator, OntarioUse of proton pump inhibitors and development of acute myocardial infarction
Project Co-LeadSafety of bowel cleansers when combined with bisacodyl stimulant laxative
Project LeadSafety of bowel cleansers when combined with bisacodyl stimulant laxative
Site Investigator, OntarioPrescription ranitidine use and population exposure in 6 Canadian provinces, 1996 to 2019: a serial cross-sectional analysis
Steering Committee LiaisonPrescription ranitidine use and population exposure in 6 Canadian provinces, 1996 to 2019: a serial cross-sectional analysis
Site Investigator, OntarioOff-label postpartum use of domperidone in Canada: a multidatabase cohort study
Steering Committee LiaisonHydrochlorothiazide use and risk of keratinocyte carcinoma and melanoma: A multisite population-based cohort study
Steering Committee LiaisonHydrochlorothiazide use and risk of keratinocyte carcinoma and melanoma: A multisite population-based cohort study
Site Investigator, OntarioIdentification of incident pancreatic cancer in Ontario administrative health data: A validation study
Collaborator, OntarioValsartan, Losartan and Irbesartan use in the USA, UK, Canada and Denmark after the nitrosamine recalls: a descriptive cohort study
Project LeadValsartan, Losartan and Irbesartan use in the USA, UK, Canada and Denmark after the nitrosamine recalls: a descriptive cohort study
Site Investigator, OntarioMethadone containing products used for opioid use disorder
Site Investigator, OntarioComparative effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists in nonvalvular atrial fibrillation: a Canadian multicentre observational cohort study
Site Investigator, OntarioEffectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi-database cohort study with meta-analysis
Site Investigator, OntarioPatterns of steroid utilization in COVID-19 patients
Site Investigator, OntarioPatterns of steroid utilization in COVID-19 patients
Project Co-LeadRisk of Arterial and Venous Thrombotic Events Among Patients with COVID-19: A Multi-National Collaboration of Regulatory Agencies from Canada, Europe, and United States
Co-Site Investigator, OntarioRisk of Arterial and Venous Thrombotic Events Among Patients with COVID-19: A Multi-National Collaboration of Regulatory Agencies from Canada, Europe, and United States
Project Co-LeadValidity of diagnoses of SARS-CoV-2 infection in Canadian administrative health data: a multiprovince, population-based cohort study
Project Co-LeadValidity of diagnoses of SARS-CoV-2 infection in Canadian administrative health data: a multiprovince, population-based cohort study
Site Investigator, OntarioComparison of pregnancy outcomes of patients treated with ondansetron vs alternative antiemetic medications in a multinational, population-based cohort
Project Co-LeadChanges in the dispensing of opioid medications in Canada following the introduction of a tamper-deterrent formulation of long-acting oxycodone: a time series analysis
Steering Committee Liaison, OntarioCoding of persistent pulmonary hypertension of the newborn in a tertiary teaching hospital: validation study
Project Co-Lead, OntarioAtypical antipsychotics and cardiomyopathy: a population-based cohort study
Project Co-Lead, OntarioThe use of atypical antipsychotics and the risk of breast cancer
Co-Site Investigator, OntarioThe use of atypical antipsychotics and the risk of breast cancer
Co-Site Investigator, OntarioUse of proton pump inhibitors and development of acute myocardial infarction
Co-Site Investigator, OntarioProton pump inhibitors and the risk of Clostridium difficile infection
Site Investigator, OntarioOutpatient Nirmatrelvir-Ritonavir and Remdesivir Utilization in Canada
Project LeadSafety of Monitoring During Use of Ozempic in People with Diabetes: A CDM Pilot Project
Project LeadOutpatient Nirmatrelvir-Ritonavir and Remdesivir Utilization in Canada
Site Investigator, OntarioUtilization Analysis of Tofacitinib and Other Drugs Among Individuals with Ulcerative Colitis: Feasibility Analysis
Site Investigator, OntarioSafety of Monitoring During Use of Ozempic in People with Diabetes: A CDM Pilot Project
Site Investigator, OntarioAssociation Between Opioid Use and the Development of Diverticulitis
Site Investigator, OntarioLong-Acting Inhalable Drugs for Chronic Obstructive Pulmonary Disease
Site Investigator, OntarioEffectiveness of PCSK9 Inhibitors in Familial Hypercholesterolemia: Feasibility Study
Project Co-LeadEffectiveness of PCSK9 Inhibitors in Familial Hypercholesterolemia: Feasibility Study
Steering Committee LiaisonEffectiveness of PCSK9 Inhibitors in Familial Hypercholesterolemia: Feasibility Study
Site Investigator, OntarioUtilization of Antidiabetic Drugs During Pregnancy: A CDM Pilot Project
Project LeadUtilization of Antidiabetic Drugs During Pregnancy: A CDM Pilot Project
Site Investigator, OntarioIntentional Self-Harm with GLP-1 Receptor Agonists for Diabetes
Project LeadIntentional Self-Harm with GLP-1 Receptor Agonists for Diabetes
Site Investigator, Ontario